Animal-Free Recombinant Human IL-1RA
货号：AF-200-01RA-20,AF-200-01RA-100,AF-200-01RA-250,AF-200-01RA-500,AF-200-01RA-1000
规格：20µg,100µg,250µg,500µg,1mg
价格：1250,2830,8080,12010,180480
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-200-01RA产品描述：Interleukin-1 receptor antagonist (IL-1RA) is a naturally-occurring, inflammatory-inhibitor protein. It inhibits the activity of IL-1α and IL-1β by competitively blocking their binding to type I and type II receptors. IL-1RA is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL-1RA may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Recombinant Human IL-1RA is a 17.2 kDa protein consisting of 153 amino acid residues.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:IL-1Ra, ICIL-1RA, IRAP, IL-1RNAA Sequence:MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDEPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to inhibit the IL-1α stimulation of murine D10S cell. The expectedED50is 20-40 ng/ml in the presence of 50 pg/ml of IL-1alpha.Calculated Molecular Weight:17.2 kDaAccession Number:P14778Gene ID:3554crossreactivity:Frog,Human,Mouse,RatCountry Of Origin:USANot for human use. |
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