Recombinant Human sTRAIL Receptor-2
货号：310-19-10,310-19-100,310-19-1000,310-19-250,310-19-50,310-19-500
规格：10ug,100ug,1mg,250ug,50ug,500ug
价格：585,3202,12850,5608,1425,8332
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins, and contain a cytoplasmic "death domain," which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane-anchored or soluble TRAIL/Apo2L. The DR4 and DR5 receptors are both produced as type I transmembrane proteins, which contain an extracellular domain, a transmembrane domain, and a cytoplasmic domain. The recombinant soluble forms of DR4 and DR5 consist of the TNFR-homologous, cysteine-rich portion of their respective extracellular domains. Recombinant Human soluble TRAIL Receptor-2/DR5 is a 14.9 kDa protein (133 amino acid residues) consisting of the TNFR-homologous, cysteine-rich portion of the extracellular domain.来源:E.coli别名:soluble TRAIL Receptor-2, DR5, TNFRSF10B, KILER, TRICK2A, TRICKB氨基酸序列:MESALITQQD LAPQQRVAPQ QKRSSPSEGL CPPGHHISED GRDCISCKYG QDYSTHWNDL LFCLRCTRCD SGEVELSPCT TTRNTVCQCE EGTFREEDSP EMCRKCRTGC PRGMVKVGDC TPWSDIECVH KES纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to inhibit apoptosis induced by Human sTRAIL/Apo2L in LN-18 cells (human glioblastoma cells).Calculated Molecular Weight:14.9 kDaAccession Number:O14763Gene ID:8795交叉反应：原产国:USA |
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