Recombinant Human IL-35
货号：200-37-10,200-37-100,200-37-1000,200-37-2,200-37-250,200-37-50,200-37-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1425,11123,44543,585,19450,6667,28897
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:Interleukin-35 is a glycosylated, disulfide-linked, heterodimeric protein consisting of the p35 subunit from IL-12 (IL-12α) and the β subunit from IL-27 (EBI3). IL-35 can be expressed by regulatory T-cells (Tregs), macrophages, and certain trophoblast and dendritic cells. It is induced in response to inflammation, and generally acts as an inflammation suppressor. IL-35 suppresses inflammation by exerting multiple activities, including the induction of regulatory T-cells and the suppression of Th17 cells. Recombinant Human IL-35 produced fromHEK293cellsis a glycosylated, heterodimeric protein that migrates as a diffuse band centered at an apparent molecular weight of about 60 kDa by SDS-PAGE analysis under non-reducing conditions. Recombinant Human IL-35 expressed inHEK293cellscontains 406 amino acid residues and has a calculated molecular weight of 45.8 kDa.别名:Interleukin-35氨基酸序列:α Subunit:RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNASβ Subunit:RKGPPAALTL PRVQCRASRY PIAVDCSWTL PPAPNSTSPV SFIATYRLGM AARGHSWPCL QQTPTSTSCT ITDVQLFSMA PYVLNVTAVH PWGSSSSFVP FITEHIIKPD PPEGVRLSPL AERQLQVQWE PPGSWPFPEI FSLKYWIRYK RQGAARFHRV GPIEATSFIL RAVRPRARYY VQVAAQDLTD YGELSDWSLP ATATMSLGK来源:HEK293 cells纯度:Greater than 90% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to inhibit proliferative activity of PBMCs.Calculated Molecular Weight:45.8 kDaAccession Number:Alpha:P29459Beta:Q14213Gene ID:Alpha:3592Beta:10148Note:50μg is the largest vial size for this product.Larger sizes supplied as multiple 50μg vials.交叉反应:Human,Mouse原产地:USA仅用于科研，不能用于临床和诊断。 |
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