Recombinant Human Apo-SAA
货号：300-13-10,300-13-100,300-13-1000,300-13-250,300-13-50,300-13-500
规格：10µg,100ug,1mg,250ug,50ug,500ug
价格：585,2308,6855,2997,1425,4446
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Human Apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of Apo-SAA, normally 1-5 μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apolipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence. Recombinant Apo-SAA is a consensus SAA molecule corresponding to human Apo-SAA1α, except for the presence of an N-terminal methionine, the substitution of asparagine for aspartic acid at position 60, and arginine for histidine at position 71 (the latter two substituted residues are present in Apo-SAA2β). The calculated molecular weight of Recombinant Human Apo-SAA is 11.7 kDa.来源:E.coli别名:Serum amyloid A protein (SAA), Serum amyloid A apolipoprotein, Amyloid fibril protein AA, TP53I4, PIG4氨基酸序列:MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 μM.** Schreiber, BM. et al.Biochem J. 1999 Nov 15; 344 Pt 1:7-13Calculated Molecular Weight:11.7 kDaAccession Number:P0DJI8Gene ID:6288交叉反应:Bacteria,Hamster,Human,Human + Mouse,Mouse,Rabbit,Rat原产地:USA仅用于科研，不能用于临床和诊断。 |
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