CD24 Monoclonal Antibody (eBioSN3 (SN3 A5-2H10)), FITC
货号：11-0247-41,11-0247-42
规格：25 Tests,100 Tests
价格：867,2127
产品类型：流式抗体
品牌：eBioscience
物种：人
宿主：小鼠
抗体亚型：IgG
克隆号：eBioSN3 (SN3 A5-2H10)
荧光染料：FITC
| 类型: | 单抗 | 同型对照： | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC |
| 浓度： | 5 µL/Test | 用法： | 5 μL (0.25 μg)/test(Flow) |
产品详细信息Description: The SN3 monoclonal antibody reacts with the human CD24 molecule, also known as Heat Stable Antigen (HSA). This 35-50 kDa molecule is anchored in the plasma membrane via phosphatidylinositol and is expressed by erythrocytes, thymocytes, peripheral lymphocytes and myeloid lineage. It has been reported that P-selectin (CD62P) binds to CD24.Applications Reported: The SN3 antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioSN3 (SN3 A5-2H10) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, andcontrol of autoimmunity.
| 数据 |
| CD24 Antibody (11-0247-41) in FlowStaining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control FITC (Product # 11-4714-42) (blue histogram) or Anti-Human CD24 FITC (purple histogram). Cells in the granulocyte gate were used for analysis. |
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| 参考文献： |
| 1.TheranosticsGlutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling."Published figure using CD24 monoclonal antibody (Product # 11-0247-42) in Flow Cytometry"2.Molecular cancerHOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells."11-0247 was used in Flow cytometry/Cell sorting to to study the role of HOXC8 regulation in breast cancer stem cells."3.OncotargetLlgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration."11-0247 was used in Flow cytometry/Cell sorting to demonstrate that loss of Llgl1 results in EGFR mislocalization, promoting pre-neoplastic changes."4.OncotargetLlgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration."11-0247 was used in Flow cytometry/Cell sorting to demonstrate that loss of Llgl1 results in EGFR mislocalization, promoting pre-neoplastic changes."5.BMC biologyThe Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states."Published figure using CD24 monoclonal antibody (Product # 11-0247-42) in Flow Cytometry"\ |
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