Anti-Human CD20 APC

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Anti-Human CD20 APC

货号:02311-80

规格:25 tests

价格:1

产品类型:细胞因子添加物

品牌:PeproTech

Description

The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.

Additional Information

Clone

2H7

Format:

APC

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG2b, kappa

Research Interest:Adaptive Immunity
Cell Type:B Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Polyak, M. J., & Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.Blood,99(9), 3256-3262.

Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

技术参数
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