Clone

AER-37 (CRA1)

Format:

FITC

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG2b, kappa

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Maurer, D., Fiebiger, E., Ebner, C., Reininger, B., Fischer, G. F., Wichlas, S., ... & Stingl, G. (1996). Peripheral blood dendritic cells express FceRI as a complex composed of FceRIa-and FceRIy-chains and can use this receptor for IgE-mediated allergen presentation.J Immunol,157, 607-616.

Yamaguchi, M., Sayama, K., Yano, K., Lantz, C. S., Noben-Trauth, N., Ra, C., ... & Galli, S. J. (1999). IgE enhances Fcε receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fcε receptor I expression and mediator release.The Journal of Immunology,162(9), 5455-5465.

Ra, C., Kuromitsu, S., Hirose, T., Yasuda, S., Furuichi, K., & Okumura, K. (1993). Soluble human high-affinity receptor for IgE abrogates the IgE-mediated allergic reaction.International immunology,5(1), 47-54.