Anti-Mouse IL-1 beta SAFIRE Purified

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Anti-Mouse IL-1 beta SAFIRE Purified

货号:82212-25-50,82212-25-500

规格:50 μg,500 μg

价格:1155,3410

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :82212-25

Description

The B122 monoclonal antibody specifically reacts with the precursor and mature secreted forms of mouse IL-1β and is cross-reactive with rat IL-1β. IL-1α and IL-1β are recognized by the same cell surface receptor but are generated from distinct genes. The B122 antibody is reported to neutralize the bioactivity of natural or recombinant IL-1β.

Additional Information

Clone

B122

Format:

SAFIRE Purified

Applications

FA, Neutralization

Reactivity

Mouse, Rat

Isotype:

Armenian Hamster IgG

Research Interest:Innate Immunity
Cell Type:Monocytes and Macrophages

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Hogquist, K. A., Nett, M. A., Sheehan, K. C., Pendleton, K. D., Schreiber, R. D., & Chaplin, D. D. (1991). Generation of monoclonal antibodies to murine IL-1 beta and demonstration of IL-1 in vivo.The Journal of immunology,146(5), 1534-1540.

Fei, R., Gott, K., Edwards, B., & Schuyler, M. (1995). Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma.The Journal of laboratory and clinical medicine,126(5), 485-494.

Miller, B. E., Krasney, P. A., Gauvin, D. M., Holbrook, K. B., Koonz, D. J., Abruzzese, R. V., ... & Ator, M. A. (1995). Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme.The Journal of Immunology,154(3), 1331-1338.

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