Anti-Human IL-4 APC

2024-10-15

Anti-Human IL-4 APC

货号:81121-80-25,81121-80-100

规格:25 tests,100 tests

价格:754,2106

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :81121-80

Description

The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.

Additional Information

Clone

MP4-25D2

Format:

APC

Applications

FC

Reactivity

Human

Isotype:

Rat IgG1, kappa

Research Interest:Innate Immunity,Adaptive Immunity, Cytokines & Growth Factors
Cell Type:T Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti‐cytokine monoclonal antibody development: immunoassay of IL‐10 and IL‐5 in clinical samples.Immunological reviews,127(1), 5-24.

Chrétien, I., Van Kimmenade, A., Pearce, M. K., Banchereau, J., & Abrams, J. S. (1989). Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4.Journal of immunological methods,117(1), 67-81.

Jung, T., Schauer, U., Rieger, C., Wagner, K., Einsle, K., Neumann, C., & Heusser, C. (1995). Interleukin‐4 and interleukin‐5 are rarely co‐expressed by human T cells.European journal of immunology,25(8), 2413-2416.

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