Anti-Mouse Notch3 APC

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Anti-Mouse Notch3 APC

货号:73312-80

规格:25 tests

价格:1320

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :73312-80

Description

The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.

Additional Information

Clone

HMN3-133

Format:

APC

Applications

FC

Reactivity

Mouse

Isotype:

Armenian Hamster IgG

Research Interest:Stem Cell Research
Cell Type:T Cells,Treg cells,Stem Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Moriyama, Y., Sekine, C., Koyanagi, A., Koyama, N., Ogata, H., Chiba, S., ... & Yagita, H. (2008). Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice.International immunology,20(6), 763-773.

Bellavia, D., Checquolo, S., Campese, A. F., Felli, M. P., Gulino, A., & Screpanti, I. (2008). Notch3: from subtle structural differences to functional diversity.Oncogene,27(38), 5092-5098.

Shi, J., Fallahi, M., Luo, J. L., & Petrie, H. T. (2011). Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.Blood,118(9), 2511-2519.

技术参数
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