Anti-Human CD85j (ILT2) SAFIRE Purified

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Anti-Human CD85j (ILT2) SAFIRE Purified

货号:62111-25

规格:100 μg

价格:3811

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :62111-25

Description

The HP-F1 monoclonal antibody reacts with human CD85j, a 110 kDA single transmembrane glycoprotein. The CD85 molecules encompass a large immunoregulatory family called Leuokocyte Immunoglobulin-like Receptors (LIRs) and Ig-Like Transcripts (ILTs). CD85j is also knows as Ig-like transcpript (ILT2) and leukocyte Ig-like receptor (LIR-1). It is expressed on subsets of NK, B and T cells and on myeloid cells such as monocytes and dendritic cells. CD85j is involved in viral infections.

Additional Information

Clone

HP-F1

Format:

SAFIRE Purified

Applications

FC, FA

Reactivity

Human

Isotype:

Mouse IgG1, kappa

Research Interest:Adaptive Immunity,Innate Immunity
Cell Type:T Cells,Monocytes and Macrophages,Dendritic Cells,NK and NKT Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Colonna, M., Navarro, F., Bellón, T., Llano, M., García, P., Samaridis, J., ... & López-Botet, M. (1997). A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells.The Journal of experimental medicine,186(11), 1809-1818.

Bellón, T., Kitzig, F., Sayós, J., & López-Botet, M. (2002). Mutational analysis of immunoreceptor tyrosine-based inhibition motifs of the Ig-like transcript 2 (CD85j) leukocyte receptor.The Journal of Immunology,168(7), 3351-3359.

Tenca, C., Merlo, A., Merck, E., Bates, E. E., Saverino, D., Simone, R., ... & Ciccone, E. (2005). CD85j (leukocyte Ig-like receptor-1/Ig-like transcript 2) inhibits human osteoclast-associated receptor-mediated activation of human dendritic cells.The Journal of Immunology,174(11), 6757-6763.

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