Anti-Human CD282 (TLR2) PE

admin 2024-10-16 34

Anti-Human CD282 (TLR2) PE

货号:24911-60-25,24911-60-100

规格:25 tests,100 tests

价格:1540,3410

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :24911-60

Description

The TL2.1 monoclonal antibody specifically reacts with human CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on peripheral blood monocytes and is involved distinguishing bacterial lipoproteins. The TL2.1 antibody blocks the receptor and immunoprecipitates TLR2 from human mammary epithelial cells (HMEC) and peripheral blood mononuclear cells (PBMC).

Additional Information

Clone

TL2.1

Format:

PE

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG2a, kappa

Research Interest:Innate Immunity
Cell Type:Monocytes and Macrophages,Dendritic Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Flo, T. H., Halaas, Ø., Lien, E., Ryan, L., Teti, G., Golenbock, D. T., ... & Espevik, T. (2000). Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.The Journal of Immunology,164(4), 2064-2069.

Lien, E., Sellati, T. J., Yoshimura, A., Flo, T. H., Rawadi, G., Finberg, R. W., ... & Golenbock, D. T. (1999). Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.Journal of Biological Chemistry,274(47), 33419-33425.

Cook, E. B., Stahl, J. L., Esnault, S., Barney, N. P., & Graziano, F. M. (2005). Toll-like receptor 2 expression on human conjunctival epithelial cells: a pathway for< i> Staphylococcus aureus</i> involvement in chronic ocular proinflammatory responses.Annals of Allergy, Asthma & Immunology,94(4), 486-497.

技术参数
© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://biorod.cn/thread-15689.htm
产品询价需求提交
最新回复 (0)
返回
发布信息
扫码添加客服微信,咨询产品报价