Anti-Mouse CD282 (TLR2) FITC

2024-10-16

Anti-Mouse CD282 (TLR2) FITC

货号:24912-50-25,24912-50-100

规格:25 μg,100 μg

价格:1430,3410

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :24912-50

Description

The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on monocytes, macrophages, dendritic cells, and the RAW264.7 cell line and is involved distinguishing bacterial lipoproteins.

Additional Information

Clone

mT2.7

Format:

FITC

Applications

FC

Reactivity

Mouse

Isotype:

Mouse IgG2a, kappa

Research Interest:Innate Immunity
Cell Type:Monocytes and Macrophages,Dendritic Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Vinnakota, K., Hu, F., Ku, M. C., Georgieva, P. B., Szulzewsky, F., Pohlmann, A., ... & Kettenmann, H. (2013). Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.Neuro-oncology,15(11), 1457-1468.

Meng, G., Rutz, M., Schiemann, M., Metzger, J., Grabiec, A., Schwandner, R., ... & Kirschning, C. J. (2004). Antagonistic antibody prevents toll-like receptor 2–driven lethal shock-like syndromes.Journal of Clinical Investigation,113(10), 1473-1481.

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