Anti-Mouse CD252 (OX40L) Biotin

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Anti-Mouse CD252 (OX40L) Biotin

货号:24611-30-25,24611-30-100

规格:25 μg,100 μg

价格:754,1839

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :24611-30

Description

The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.

Additional Information

Clone

RM134L

Format:

Biotin

Applications

FC

Reactivity

Mouse

Isotype:

Rat IgG2b, kappa

Research Interest:Adaptive Immunity
Cell Type:B Cells,Dendritic Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted biotin was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Stüber, E., Neurath, M., Calderhead, D., Perry Fell, H., & Strober, W. (1995). Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells.Immunity,2(5), 507-521.

Akiba, H., Oshima, H., Takeda, K., Atsuta, M., Nakano, H., Nakajima, A., ... & Okumura, K. (1999). CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells.The Journal of Immunology,162(12), 7058-7066.

Calderhead, D. M., Buhlmann, J. E., Van den Eertwegh, A. J., Claassen, E., Noelle, R. J., & Fell, H. P. (1993). Cloning of mouse Ox40: a T cell activation marker that may mediate TB cell interactions.The Journal of Immunology,151(10), 5261-5271.

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