Anti-Mouse CD127 (IL-7Ra) FITC

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Anti-Mouse CD127 (IL-7Ra) FITC

货号:19212-50-25,19212-50-100

规格:25 μg,100 μg

价格:471,1509

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :19212-50

Description

The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.

The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.

Additional Information

Clone

A7R34

Format:

FITC

Applications

FC

Reactivity

Mouse

Isotype:

Rat IgG2a, kappa

Research Interest:Adaptive Immunity
Cell Type:B Cells,T Cells,Treg cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Sudo, T., Nishikawa, S. A. T. O. M. I., Ohno, N. O. R. I. K. O., Akiyama, N. A. O. K. O., Tamakoshi, M. A. S. A. T. A. D. A., & Yoshida, H. I. S. A. H. I. R. O. (1993). Expression and function of the interleukin 7 receptor in murine lymphocytes.Proceedings of the National Academy of Sciences,90(19), 9125-9129.

Hashi, H., Yoshida, H., Honda, K., Fraser, S., Kubo, H., Awane, M., ... & Nishikawa, S. I. (2001). Compartmentalization of Peyer’s patch anlagen before lymphocyte entry.The Journal of Immunology,166(6), 3702-3709.

Okuno, Y., Iwasaki, H., Huettner, C. S., Radomska, H. S., Gonzalez, D. A., Tenen, D. G., & Akashi, K. (2002). Differential regulation of the human and murine CD34 genes in hematopoietic stem cells.Proceedings of the National Academy of Sciences,99(9), 6246-6251.

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