Anti-Mouse CD69 FITC

admin 2024-10-16 12

Anti-Mouse CD69 FITC

货号:11712-50-25,11712-50-100

规格:25 ug,100 μg

价格:550,1430

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :11712-50

Description

The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.

C57Bl/6 splenocytes were stimulated overnight with Concanavalin A and stained with FITC H1.2F3 with relevant isotype control in Red.

Additional Information

Clone

H1.2F3

Format:

FITC

Applications

FC

Reactivity

Mouse

Isotype:

Armenian Hamster IgG

Research Interest:Adaptive Immunity
Cell Type:B Cells,NK and NKT Cells,T Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., & Corradin, S. B. (1997). Expression and function of the early activation antigen CD69 in murine macrophages.Journal of leukocyte biology,62(3), 349-355.

Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., & Shevach, E. M. (1988). Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.The Journal of Immunology,141(2), 369-376.

Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., & Cohen, P. L. (1993). Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.The Journal of Immunology,150(2), 673-682.

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