Anti-Rat CD28 PE

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Anti-Rat CD28 PE

货号:10313-60 -50,10313-60 -200

规格:50 ug,200 ug

价格:1100,3410

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalog Number :10313-60

Description

The JJ319 monoclonal antibody specifically reacts with rat CD28, a 44 kDa glycoprotein member of the immunoglobulin superfamily. CD28 is expressed on alpha/beta TCR+ T cells, some gamma/delta TCR+ T cells and a subset of NK cells. CD28 is a costimulatory receptor required for T cell activation. Its ligands are CD80 (B7-1) and CD86 (B7-2).

Additional Information

Clone

JJ319

Format:

PE

Applications

FC

Reactivity

Rat

Isotype:

Mouse IgG1

Research Interest:Adaptive Immunity
Cell Type:T Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Tacke, M., Clark, G. J., Dallman, M. J., & Hünig, T. (1995). Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of costimulated T cell responses by phorbol ester.The Journal of Immunology154(10), 5121-5127.

Tacke, M., Hanke, G., Hanke, T. H T. (1997). CD28‐mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: Evidence for functionally distinct forms of CD28.European journal of immunology27(1), 239-247.

Bluestone, J. A. (1995). New perspectives of CD28-B7-mediated T cell costimulation.Immunity,2(6), 555-559.

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