CD152CTLA-4MonoclonalAntibody14D3FunctionalGradeeBioscienceCD152CTLA-4单抗14D3功能抗体eBioscience

货号：16-1529-82,16-1529-025,16-1529-050

规格：100ug,25mg,50mg

价格：3025,0,0

产品类型：流式抗体

品牌：eBioscience

抗原：CD152

物种：其它

宿主：小鼠

抗体亚型：IgG2a, kappa

克隆号：14D3

荧光染料：Purified

tablewidth684cellspacing0cellpadding0tbodytrclassfirstRowtdwidth77styleborder-colorrgb216216216backgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4styletext-aligncentermargin-top5pxmargin-bottom5pxspanstylefont-familyarialhelveticasans-seriffont-size14px抗体类型spanh4tdtdwidth247styleborder-leftmediumnonecurrentcolorborder-top-colorrgb216216216border-right-colorrgb216216216border-bottom-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4styletext-aligncentermargin-top5pxmargin-bottom5pxspanstylefont-familyarialhelveticasans-seriffont-size14px流式抗体spanh4tdtdwidth79styleborder-leftmediumnonecurrentcolorborder-top-colorrgb216216216border-right-colorrgb216216216border-bottom-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4styletext-aligncentermargin-top5pxmargin-bottom5pxspanstylefont-familyarialhelveticasans-seriffont-size14px同型对照spanh4tdtdwidth279styleborder-leftmediumnonecurrentcolorborder-top-colorrgb216216216border-right-colorrgb216216216border-bottom-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4stylemargin-top5pxmargin-bottom5pxahrefhttpwwwnwbioteccomindexphpgmProductaprdtid14161target_selfspanstylefont-size14pxMouseIgG2akappaIsotypeControleBM2aFunctionalGradeeBiosciencespanah4tdtrtrtdwidth78styleborder-topmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-left-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4styletext-aligncentermargin-top5pxmargin-bottom5pxspanstylefont-familyarialhelveticasans-seriffont-size14px浓度spanh4tdtdwidth247styleborder-topmediumnonecurrentcolorborder-leftmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4stylemargin-top5pxmargin-bottom5pxspanstylefont-familyarialhelveticasans-seriffont-size14pxnbspnbspnbspnbspnbspnbspnbspnbspspanspanstylefont-size14pxnbspnbsp1mgmLspanh4tdtdwidth79styleborder-topmediumnonecurrentcolorborder-leftmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4styletext-aligncentermargin-top5pxmargin-bottom5pxspanstylefont-familyarialhelveticasans-seriffont-size14px用法spanh4tdtdwidth279styleborder-topmediumnonecurrentcolorborder-leftmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14px025gtestnbspFlowspanh4tdtrtbodytableh4stylefont-variant-numericnormalfont-variant-east-asiannormalwhite-spacenormalspanstylefont-familyarialhelveticasans-seriffont-size14pxspanh4h4stylefont-variant-numericnormalfont-variant-east-asiannormalmargin-bottom5pxmargin-top5pxwhite-spacenormalspanstylefont-size14pxspanh4h4stylemargin5px0pxcolorinheritline-height17pxfont-familyHelveticaNeueLT-BoldquotHelveticaNeuequotHelveticaRobotoquotSegoeUIquotArialsans-seriffont-size14pxbox-sizingborder-boxspanstylefont-familyarialhelveticasans-serif产品详细信息nbspspanbrh4h4stylemargin5px0pxline-height14285box-sizingborder-boxspanstylefont-size14pxfont-familyarialhelveticasans-serifDescriptionspanh4h4stylebox-sizingborder-boxmargin-top5pxmargin-bottom5pxline-height142857importantspanstylefont-size14pxfont-familyarialhelveticasans-serifspanh4h4stylebox-sizingborder-boxmargin-top5pxmargin-bottom5pxline-height142857importantspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylebox-sizingborder-boxmargin-top5pxmargin-bottom5pxline-height142857importantspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxThe14D3monoclonalantibodyreactswithhumanCD152alsoknownascytotoxicTlymphocyteantigen-4CTLA-4CTLA-4aproteinwithstructuralsimilaritiestoCD28isexpressedonactivatedTcellsactivatedBcellsmayalsoexpressCTLA-4andbindstheB7familymembersCD80B7-1andCD86B7-2withhigheraffinitythanCD28doesCTLA-4andCD28appeartodeliveropposingsignalstoTcellswhileCD28isapotentcostimulatorCTLA-4restrictstheprogressionofTcellsnbsptoanactivatedstatebyinhibitingIL-2secretionandcellularproliferationThecytoplasmicportionofCTLA-4containsERretentionmotifsresultinginintracellularlocalizationofalargeproportionofnewlysynthesizedCTLA-4inresponsetoTCRsignalingbrstylebox-sizingborder-boxThe14D3antibodyalsorecognizesrhesusmonkeyandhasinhibitoractivitybrstylebox-sizingborder-boxApplicationsReportedThe14D3antibodyhasbeenreportedforuseinflowcytometricanalysisIthasalsobeenreportedininvitroinhibitionstudiesPleaseuseFunctionalGradepurified14D3infunctionalassaysbrstylebox-sizingborder-boxApplicationsTestedThe14D3antibodyhasbeentestedbyflowcytometricanalysisofPHAstimulatednormalhumanperipheralbloodcellsThiscanbeusedatlessthanorequalto025gpertestAtestisdefinedastheamountgofantibodythatwillstainacellsampleinafinalvolumeof100LCellnumbershouldbedeterminedempiricallybutcanrangefrom105to108cellstestItisrecommendedthattheantibodybecarefullytitratedforoptimalperformanceintheassayofinterestbrstylebox-sizingborder-boxFurthermoreduetotheintracellularlocalizationofalargeportionofCTLA-4forcompletedetectionitmaybenecessarytoassessintracellularexpressioninadditiontosurfaceexpressionofCTLA-4brstylebox-sizingborder-boxStorageandhandlingUseinasterileenvironmentbrstylebox-sizingborder-boxFiltration02mpost-manufacturingfilteredbrstylebox-sizingborder-boxPurityGreaterthan90asdeterminedbySDS-PAGEbrstylebox-sizingborder-boxEndotoxinLevelLessthan0001nggantibodyasdeterminedbyLALassaybrstylebox-sizingborder-boxAggregationLessthan10asdeterminedbyHPLCspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxTargetInformationspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxCTLA4CytotoxicT-LymphocyteAntigen4isaCD28-familyreceptorexpressedonmainlyCD4TcellsItbindsthesameligandsasCD28CD80andCD86onBcellsanddendriticcellsbutwithhigheraffinitythanCD28HoweverincontrasttoCD28whichenhancescellfunctionwhenboundatthesametimeastheTcellreceptorCTLA4inhbitstheTcellandpreventsitfromfunctioningIntracellularCTLA4isalsofoundinregulatoryTcellsandmaybeimportanttotheirfunctionspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxForResearchUseOnlyNotforuseindiagnosticproceduresNotforresalewithoutexpressauthorizationspanh4tablewidth684cellspacing0cellpadding0tbodytrclassfirstRowtdstyleborder-topmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-left-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxfont-familyarialhelveticasans-serif数据spanh4tdtrtrtdstyleborder-topmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-left-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxwhitepstyletext-aligncenterimgsrchttpwwwnwbioteccomdatauploadueditor2021042860890df26447apngtitleimagepngaltimagepngph4stylemargin-bottom5pxmargin-top5pxh4h4stylemargin-top5pxmargin-bottom5pxh4h4stylemargin5px0pxfont-familyHelveticaNeueLT-BoldquotHelveticaNeuequotHelveticaRobotoquotSegoeUIquotArialsans-seriffont-weight400line-height26pxcolorrgb343434letter-spacing05pxfont-size22pxbox-sizingborder-boxwhite-spacenormalspanstylecolorrgb000font-size14pxfont-familyarialhelveticasans-serifspanh4h4stylemargin5px0pxfont-familyHelveticaNeueLT-BoldquotHelveticaNeuequotHelveticaRobotoquotSegoeUIquotArialsans-seriffont-weight400line-height26pxcolorrgb343434letter-spacing05pxfont-size22pxbox-sizingborder-boxwhite-spacenormalspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-top5pxmargin-bottom5pxspanstylefont-size14pxspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxCD152CTLA-4Antibody16-1529-82spanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxOncotarget2017-nbspPublishedfigureusingCD152CTLA-4monoclonalantibodyspanspanstylefont-size14pxProduct16-1529-82spanspanstylefont-size14pxspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxspanh4tdtrtrtdstyleborder-topmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-left-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxrgb242242242h4stylemargin-bottom5pxmargin-top5pxstrongspanstylefont-family宋体font-weightnormal推荐产品spanstrongh4tdtrtrtdstyleborder-topmediumnonecurrentcolorborder-right-colorrgb216216216border-bottom-colorrgb216216216border-left-colorrgb216216216border-imagenone10010stretchbackgroundnone00autorepeatscrollpadding-boxborder-boxwhiteh4stylemargin-top5pxmargin-bottom5pxspanstylefont-familyArialsans-seriffont-size14pxfont-weightnormalfont-variant-numericnormalfont-variant-east-asiannormalspanh4h4stylewhite-spacenormalmargin-top5pxmargin-bottom5pxstrongspanstylefont-familyArialletter-spacing0pxfont-size14pxahrefhttpwwwnwbioteccomindexphpgmcategoryasearchtypetwoid137二抗aspanstrongh4h4stylewhite-spacenormalmargin-top5pxmargin-bottom5pxstrongspanstylefont-familyArialletter-spacing0pxfont-size14pxahrefhttpwwwnwbioteccomindexphpgmcategoryasearchtypetwoid159荧光二抗aspanstrongh4h4stylewhite-spacenormalmargin-top5pxmargin-bottom5pxstrongspanstylefont-familyArialletter-spacing0pxfont-size14pxahrefhttpwwwnwbioteccomindexphpgmcategoryasearchtypetwoid158免疫组化一抗aspanstrongh4h4stylewhite-spacenormalmargin-top5pxmargin-bottom5pxstrongspanstylefont-familyArialletter-spacing0pxfont-size14pxahrefhttpwwwnwbioteccomindexphpgmcategoryasearchtypetwoid173标签抗体aspanstrongh4tdtrtrtdcolspan1rowspan1styleborder-top-colorrgb216216216border-left-colorrgb216216216background-colorrgb242242242参考文献tdtrtrtdcolspan1rowspan1h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14px1Naturecommunicationsspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxFollicularregulatoryTcellsimpairfollicularThelpercellsinHIVandSIVinfectionspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxquotPublishedfigureusingCD152CTLA-4monoclonalantibodyProduct16-1529-82inFlowCytometryquotspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14px2Journalofvirologyspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxEfficientNef-mediateddownmodulationofTCR-CD3andCD28isassociatedwithhighCD4TcellcountsinviremicHIV-2infectionspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxquot16-1529wasusedinFlowcytometryCellsortingtoelucidatetheroleoftheNefproteininenhancingfunctionalityofimmunecellsandintheimmunopathogenesisofHIV-2infectionquotspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14px3Scientificreportsspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxOnetwoorthreeProbingthestoichiometryofmembraneproteinsbysingle-moleculelocalizationmicroscopyspanh4h4stylemargin-bottom5pxmargin-top5pxspanstylefont-size14pxquot16-1529wasusedinFlowcytometryCellsortingtodemonstratetheuseofasingle-moleculecountingstrategyinexploringstoichiometryofmembraneproteinsquotspanh4tdtrtbodytablepstylefont-variant-numericnormalfont-variant-east-asiannormalwhite-spacenormalbrppbrstylewhite-spacenormalppbrp

技术参数

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://biorod.cn/thread-15881.htm