ANTI-HUMAN CD19 (HIB19) FITC

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ANTI-HUMAN CD19 (HIB19) FITC

货号:11-0199-41,11-0199-42

规格:25TESTS,100 TESTS

价格:835,1978

产品类型:流式抗体

品牌:eBioscience

抗原:CD19

物种:人

宿主:小鼠

抗体亚型:IgG

克隆号: HIB19

荧光染料:FITC

抗体类型:单抗同型对照:IgG1, kappa
免疫原性:用法:5 µL (1 µg)/test(Flow)
Description: The HIB19 monoclonal antibody reacts with human CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, Leu13, MHC class II, and CD19 form a multimolecular complex that associates with BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells. The SJ25C1 antibody and the HIB19 monoclonal antibody recognize overlapping epitopes.Applications Reported: The HIB19 antibody has been reported for use in flow cytometric analysis.Applications Tested: This HIB19 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered.
数据

CD19 Antibody (11-0199-41) in Flow

Staining of normal human peripheral blood cells with Anti-Human

CD3 PE (Product # 12-0038-42) and Anti-Human CD19 FITC.

推荐产品:
Flow Cytometry Staining Buffer, eBioscienceUltracomp eBeads microspheresLIVE/DEAD® Fixable Cell Stains
参考文献:
1.eLifeILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation."11-0199 was used in Flow cytometry/Cell sorting to investigate how a small population of innate lymphoid cells (ILCs) has large effects on immune homeostasis, showing that ILC3s produce GM-CSF to orchestrate acute intestinal inflammation."Authors Pearson C,Thornton EE,McKenzie B,Schaupp AL,Huskens N,Griseri T,West N,Tung S,Seddon BP,Uhlig HH,Powrie F2.Acta neuropathologicaPeripheral monocytes are functionally altered and invade the CNS in ALS patients."11019942 was used in flow cytometry to find that central nervous system infiltration of peripheral monocytes correlates with improved motor neuron survival in a genetic amyotrophic lateral sclerosis mouse model"Authors Zondler L,Müller K,Khalaji S,Bliederhäuser C,Ruf WP,Grozdanov V,Thiemann M,Fundel-Clemes K,Freischmidt A,Holzmann K,Strobel B,Weydt P,Witting A,Thal DR,Helferich AM,Hengerer B,Gottschalk KE,Hill O,Kluge M,Ludolph AC,Danzer KM,Weishaupt JH3.OncotargetHeightened BTK-dependent cell proliferation in unmutated chronic lymphocytic leukemia confers increased sensitivity to ibrutinib."11-0199 was used in Flow cytometry/Cell sorting to demonstrate the reduced prognostic significance of immunoglobulin heavy-chain variable region gene mutation in the light of new therapies."Authors Guo A,Lu P,Galanina N,Nabhan C,Smith SM,Coleman M,Wang YL4.Stem cell reportsMIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia."11-0199 was used in Flow cytometry/Cell sorting to show MIF plays a role in regulating the differentiation fate of human cartilage endplate stem cells under hypoxia."Authors Yao Y,Deng Q,Song W,Zhang H,Li Y,Yang Y,Fan X,Liu M,Shang J,Sun C,Tang Y,Jin X,Liu H,Huang B,Zhou Y5.PloS oneThe Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis."11-0199 was used in Flow cytometry/Cell sorting to assess specific B cell functional interaction following stimulation with a broad range of antigens within the LTBI milieu."Authors du Plessis WJ,Kleynhans L,du Plessis N,Stanley K,Malherbe ST,Maasdorp E,Ronacher K,Chegou NN,Walzl G,Loxton AG

技术参数

产品应用 Flow;IF

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