CD3 Monoclonal Antibody (OKT3), Alexa Fluor 488, eBioscience™
货号：53-0037-41,53-0037-42
规格：25TESTS,100TESTS
价格：1112,2583
产品类型：流式抗体
品牌：eBioscience
抗原：CD3
物种：人
宿主：小鼠
抗体亚型：IgG
克隆号：OKT3
荧光染料：Alexa Fluor 488
| 抗体类型: | 单抗 | 同型对照： | IgG2a, kappa |
| 免疫原性： | | 用法： | 5uL（1 µg）/test(Flow） |
| Description: The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.Applications Reported: This OKT3 antibody has been reported for use in flow cytometric analysis.Applications Tested: This OKT3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered. |
| 数据 |
CD3 Antibody (53-0037-41) in FlowStaining of normal human peripheral blood cells with Anti-Human CD19 PE (Product # 12-0199-80) and staining buffer (autofluorescence) (left) or Anti-Human CD3 Alexa Fluor® 488 (right). Cells in the lymphocyte gate were used for analysis. |
| 推荐产品： |
| 免疫细胞分选CD3流式抗体细胞因子细胞周期检测细胞凋亡检测细胞增殖活性检测 |
| 参考文献： |
| 1.PloS one HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA). "53-0037 was used in Flow cytometry/Cell sorting to evaluate whether cellular activation can be induced by HIV itself, showing that gp120 activates LFA-1 on CD4 T-lymphocytes." Authors Hioe CE,Tuen M,Vasiliver-Shamis G,Alvarez Y,Prins KC,Banerjee S,Nádas A,Cho MW,Dustin ML,Kachlany SC |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-16667.htm
QQ:1749072012