Lamin A/C Monoclonal Antibody (mab636)/Lamin A/C内参抗体
货号：MA3-1000
规格：200 µL
价格：4223
产品类型：内参抗体
品牌：Thermo Fisher
物种：人
宿主：小鼠
抗体亚型：其它
荧光染料：其它
点击Invitrogen内参抗体集，查看更多内参抗体
抗体类型: | 单抗 | 同型对照： | IgG2b |
免疫原性： | Porcine lamin preparation. | 用法： | 1:100（ICC）;1:100（IF）;1:100（IHC(F)）;1:100 - 1:2000(WB) |
Product Specific InformationMA3-1000 detects lamin A/C from human, bovine, porcine and canine samples.MA3-1000 has been successfully used in Western blot, immunofluorescence and immunohistochemistry procedures. By Western blot, this antibody detects ~ 70 and 65 kDa proteins corresponding to lamin A and C, respectively, from HeLa cell extract. This antibody can also be used for immunofluorescence and immunohistochemistry for subcellular localization experiments. MA3-1000 has been widely used for detection of lamin A/C control in siRNA experiments.The MA3-1000 antigen is porcine lamin preparation.Background/Target InformationLamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD),limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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