OCT4 Recombinant Rabbit Monoclonal Antibody (3H8L1.12)
货号：703927
规格：100 µg
价格：4575
产品类型：免疫组化一抗
品牌：Thermo Fisher
抗原：OCT4
物种：人
宿主：兔
抗体亚型：IgG
克隆号：9B7
荧光染料：其它
| 类型: | 单抗 | 同型对照： | |
| 浓度： | 0.5 mg/mL | 用法： | 1:5,000(WB)；1:16,000(ICC/IF) |
产品详细信息This antibody is predicted to react with Mouse.靶标信息POU5F1, also commonly known as Oct-4, is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. The role of POU5F1 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing POU5F1, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
QQ:1749072012