SSEA4 Monoclonal Antibody (MC813-70)

货号：41-4000

规格：100 µg

价格：4809

产品类型：流式抗体

品牌：Thermo Fisher

抗原：SSEA4

物种：人/小鼠

宿主：小鼠

抗体亚型：其它

克隆号：MC813-70

荧光染料：Purified

类型:	单抗	同型对照：	IgG3
免疫原性：	Human SSEA4 antigen	用法：

Target InformationSSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

数据

SSEA4 Antibody (41-4000) in FlowHistogram from flow cytometric analysis of NTERA-2 cells stained with either SSEA4 Monoclonal Antibody, Mouse (clone MC813-70) (Product # 41-4000) (black line) or mouse IgG isotype control (gray line) followed by detection with fluorescein-conjugated goat anti-mouse IgG (Product # M32601). SSEA4 Antibody (41-4000) in IFImmunofluoroscent analysis of Shef 4 Human ES cell line using mouse anti-SSEA4 antibody (Product # 41-4000).

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参考文献：

1.Cell regeneration (London, England)GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment.2.Journal of tissue engineeringCharacterization of the structure, cells, and cellular mechanobiological response of human plantar fascia.3.OncotargetA novel bioactive osteogenesis scaffold delivers ascorbic acid, β-glycerophosphate, and dexamethasone in vivo to promote bone regeneration.4.Stem cells internationalDifferential Characterization of Two Kinds of Stem Cells Isolated from Rabbit Nucleus Pulposus and Annulus Fibrosus.5.Folia biologicaX-Chromosome Inactivation Analysis in Different Cell Types and Induced Pluripotent Stem Cells Elucidates the Disease Mechanism in a Rare Case of Mucopolysaccharidosis Type II in a Female."41-4000 was used in immunocytochemistry to elucidate the mechanism responsible for a rare case of a female with mucopolysaccharidosis type II via X-chromosome inactivation analysis in different cell types and induced pluripotent stem cells"AuthorsŘeboun M,Rybová J,Dobrovolný R,Včelák J,Veselková T,Štorkánová G,Mušálková D,Hřebíček M,Ledvinová J,Magner M,Zeman J,Pešková K,Dvořáková L

技术参数

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