VAP-1 Monoclonal Antibody (TK8-14), eBioscience/VAP-1单克隆抗体（TK8-14）

货号：BMS1033

规格：100 µg

价格：3679

产品类型：流式抗体

品牌：eBioscience

物种：人

宿主：小鼠

抗体亚型：其它

克隆号：TK8-14

荧光染料：其它

类型:	单抗	同型对照：
浓度：	1 mg/mL	用法：	Assay-Dependent（ELISA)；Assay-Dependent(Flow)；Assay-Dependent(IHC)；Assay-Dependent(WB)

产品详细信息Description: VAP-1 (TK8-14) is a mouse monoclonal antibody raised against affinity purifiedVAP-1 from tonsil stroma of human origin.Lymphocyte binding to vascular endothelium is a prerequisite for the move-ment of immune cells from the blood into lymphoid tissues and into sites ofinflammation. Under inflammatory conditions, cell surface expression ofVAP-1 (vascular adhesion protein-1) which is an endothelial sialoglycoprotein,is induced. VAP-1 is a type II transmembrane protein of 84.6 kDa with a singletransmembrane domain and N and O-glycosylation sites in the extracellulardomain. In vivo, VAP-1 exists predominantly as a 180 kDa homodimer andfunctions both as an enzyme (monoamine oxidase) and an adhesion moleculefor lymphocytes.Applications Tested: ELISA, Flow Cytometry, Immunofluorescence, Western Blotting.靶标信息Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.

数据

VAP-1 Antibody (BMS1033)The Journal of clinical investigation 2015 -Published figure using VAP-1 monoclonal antibody (Product # BMS1033) VAP-1 Antibody (BMS1033)The Journal of clinical investigation 2015 -Published figure using VAP-1 monoclonal antibody (Product # BMS1033)

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流式抗体

参考文献：

1. The Journal of clinical investigationVascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.2. The Journal of clinical investigationVascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.

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