Nkx2.5 Recombinant Rabbit Monoclonal Antibody (4H5L9)
货号：701622
规格：100 µg
价格：4809
产品类型：免疫组化一抗
品牌：eBioscience
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
类型: | 单抗 | 同型对照： | |
浓度： | 0.5 mg/mL | 用法： | Assay Dependent (ICC) |
免疫原性： | human Nkx2. |
产品详细信息Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. 靶标信息NKX2-5 is a transcription factor protein which plays a crucial role in cardiac development and differentiation. It is a low molecular weight protein of 35-38 kDa depending on phosphorylation status. Expression is mainly restricted to the heart. But during embryogenesis NKX2-5 expression has also been detected in spleen-precursor cells. Over expression of NKX2-5 resulted in expression of neuronal markers in C2C12 murine myogenic cells. Functionally it is involved in differentiation processes in heart development and in homeostasis and survival of cardiac myocytes as well maintains the initial muscle differentiation paradigm.
数据 |
| Nkx2.5 Antibody (701622) in IF Immunocytochemistry analysis of Human cardiomyocytes stained with Nkx2.5 Recombinant Rabbit Monoclonal Antibody (Product # 701622, 5.0 µg/mL) using a: Alexa Fluor® 488 Goat anti-Rabbit as a secondary antibody (green). b: DAPI stained Primary human cardiomyocytes nuclei (blue). c: Actin stained with Alexa Fluor® 594 Phalloidin (red). d: composite image of cells showing nuclear localization. e: No primary control. |
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| 二抗荧光二抗免疫组化一抗标签抗体 |
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