VAP-1 Monoclonal Antibody (TK8-18), eBioscience/VAP-1单克隆抗体(TK8-18)

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VAP-1 Monoclonal Antibody (TK8-18), eBioscience/VAP-1单克隆抗体(TK8-18)

货号:BMS1034

规格:100 µg

价格:3679

产品类型:抗体和ELISA

品牌:eBioscience

类型:

单抗

同型对照:

浓度:

1 mg/mL

用法:

Assay-Dependent(ELISA);Assay-Dependent(WB)
产品详细信息Description: Lymphocyte binding to vascular endothelium is a prerequisite for the move-ment of immune cells from the blood into lymphoid tissues and into sites ofinflammation. Under inflammatory conditions, cell surface expression ofVAP-1 (vascular adhesion protein-1) which is an endothelial sialoglycoprotein,is induced. VAP-1 is a type II transmembrane protein of 84.6 kDa with a singletransmembrane domain and N and O-glycosylation sites in the extracellulardomain. In vivo, VAP-1 exists predominantly as a 180 kDa homodimer andfunctions both as an enzyme (monoamine oxidase) and an adhesion moleculefor lymphocytes.Applications Tested: ELISA, Western Blotting.靶标信息Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.

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