HAT1 Polyclonal Antibody

货号：PA5-96526

规格：100 µL

价格：4732

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant fusion protein containing a sequence c

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1.49 mg/mL	用法：	1:100-1:500(Flow) ;4-6 µg/mL(IHC(P));2-4 µg/mL(WB)

产品详细信息Immunogen sequence: TPFQGQGHGA QLLETVHRYY TEFPTVLDIT AEDPSKSYVK LRDFVLVKLC QDLPCFSREK LMQGFNEDMA IEAQQKFKIN KQHARRVYEI LRLLVTDMSD AEQYRSYRLD IKRRLISPYK KKQRDLAKMR KCLRPEELTN QMNQIEISMQ HEQLEESFQE LVEDYRRVIE RLAQE; Positive Samples: MCF7, SW480, Jurkat, 293T, HeLa, HepG2, U-251MG, Mouse spleen, Rat testis; Cellular Location: Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm 靶标信息The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

数据：

HAT1 Antibody (PA5-96526) in IHCImmunohistochemistry analysis of HAT1 in paraffin-embedded mouse osteosarcoma using HAT1 Polyclonal Antibody (Product # PA5-96526) at a dilution of 1:200. HAT1 Antibody (PA5-96526) in WBWestern Blot analysis of HAT1 in extracts of various cell lines using HAT1 Polyclonal Antibody (Product # PA5-96526) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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