HAT1 Polyclonal Antibody

货号：PA5-57817

规格：100 µL

价格：5548

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human HAT1

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.1 mg/mL	用法：	0.25-2 µg/mL(ICC) ;0.25-2 µg/mL(IF);1:200-1:500(IHC);0.04-0.4 µg/mL(WB)

产品详细信息Immunogen sequence: KFKINKQHAR RVYEILRLLV TDMSDAEQYR SYRLDIKRRL ISPYKKKQRD LAKMRKCLRP EELTNQMNQI EISMQHEQLE ESFQELVEDY RRVIERLAHighest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%. 靶标信息The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

数据：

Phospho-PKC theta (Thr538) Antibody (700043) in IHC (P) Immunohistochemistry analysis of Phospho-PKC theta pThr538 in formalin-fixed, paraffin-embedded human breast carcimona tissue using a Phospho-PKC theta pThr538 monoclonal antibody (Product # 700043) at a dilution of 5 µg/mL. Staining was visualized using DAB. Images were taken at a magnification of 20x. Results show cytoplasmic staining in tumor cells. HAT1 Antibody (PA5-57817) in IHCImmunohistochemical staining of HAT1 in human lymph node shows strong nuclear positivity in germinal center cells. Samples were probed using a HAT1 Polyclonal Antibody (Product # PA5-57817).

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