Human GFR alpha-1/GDNF R ELISA Kit/人GFR alpha-1 / GDNF R ELISA试剂盒
货号：EH217RB,EH217RBX5,EH217RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6327,28472,54564
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.35 ng/mL |
| 检测范围 | 0.35-80 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | GFR alpha-1 |
| Protein aliases | GDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, Glial cell line-derived neurotrophic factor receptor alpha, GPI-linked anchor protein, PI-linked cell-surface accessory protein, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | GDNFR, GDNFRA, GFR-ALPHA-1, GFRA1, RET1L, RETL1, TRNR1 |
| Gene ID | (Human) 2674 |
| Gene symbol | GFRA1 |
| UniProt ID | (Human) P56159 |
| Human GFR alpha-1/GDNF R quantitates human GFR alpha-1/GDNF R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GFR alpha-1/GDNF R.人GFR alpha-1 / GDNF R定量测定血清，血浆，上清液中的人GFR alpha-1 / GDNFR。 该检测试剂盒将专门识别天然和重组人GFR alpha-1 / GDNFR。Target information 靶标信息Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFR-a-1 recently. GFR-a-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFR-a and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.胶质细胞源性神经营养因子（GDNF）是中枢神经和外周神经元的有效存活因子，对肾脏和肠神经系统的发育至关重要。 对GDNF的生理反应需要存在一种新的糖基磷酸二甘油肌醇连接蛋白GDNFRalpha，它是GDNF的细胞表面受体。 最近已经克隆了来自人，大鼠，鸡和小鼠的编码GDNFRalpha的cDNA。 GDNFRalpha也被称为Ret配体1（RETL1）或TGF-beta相关的神经营养因子受体1（TrnR1），最近被命名为GFR-a-1。 GFR-a-1特异性结合GDNF并介导Ret蛋白酪氨酸激酶（PTK）的激活。 因此，GDNF，GFR-α和Ret PTK形成复合物以转导GDNF信号并介导GDNF功能。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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