JMJD2C Monoclonal Antibody (OTI5B9)
货号:MA5-24956
规格:100 µL
价格:5956
产品类型:标签抗体
品牌:Thermo Fisher
抗原:Full-length protein expressed in 293T cell transfe
物种:人
宿主:小鼠
抗体亚型:IgG1, kappa
克隆号:OTI5B9
荧光染料:其它
类型: | 一抗 | 同型对照: | |
浓度: | 1 mg/mL | 用法: | 1:100(ICC);1:100(IF);1:50(IHC(P));1:2000(WB) |
产品详细信息Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 "Lys-9' and H3 "Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.
数据: |
JMJD2C Antibody (MA5-24956) in ICCImmunofluorescent analysis of KDM4C in COS7 cells. Cells were transfected with a plasmid overexpressing KDM4C and probed with a KDM4C monoclonal antibody (Product # MA5-24956). JMJD2C Antibody (MA5-24956) in IHC (P)Immunohistochemistry was performed on paraffin-embedded ovary tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a KDM4C monoclonal antibody (Product # MA5-24956) at a dilution of 1:50.JMJD2C Antibody (MA5-24956) in WBWestern blot analysis of KDM4C in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with KDM4C (Product # MA5-24956) monoclonal antibody. |
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