JMJD2C Polyclonal Antibody

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JMJD2C Polyclonal Antibody

货号:PA5-23065

规格:100 µL

价格:5930

产品类型:标签抗体

品牌:Thermo Fisher

抗原:A synthetic peptide made to an internal region of

物种:人/小鼠

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 0.5 mg/mL用法:1:100(ICC);1:100(IF);1:100(IHC(P));1:10000(WB)
产品详细信息Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.靶标信息Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 "Lys-9' and H3 "Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.
数据:

JMJD2C Antibody (PA5-23065) in IFImmunofluorescent analysis of JMJD2C using a polyclonal antibody (Product # PA5-23065).

JMJD2C Antibody (PA5-23065) in IHCImmunohistochemical analysis of JMJD2C using a polyclonal antibody (Product # PA5-23065).

JMJD2C Antibody (PA5-23065) in WBWestern blot analysis of JMJD2C using a polyclonal antibody (Product # PA5-23065).
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