Canine GM-CSF ELISA Kit/犬GM-CSF ELISA试剂盒
货号：EC5RB,EC5RBX5,EC5RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：其它
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.13 ng/mL |
| 检测范围 | 0.13-25 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | GM-CSF |
| Protein aliases | Colony-stimulating factor, CSF, GM-CSF, Granulocyte-macrophage colony-stimulating factor |
物种（Tested） | 狗 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CSF2, GM-CSF |
| Gene ID | (Dog) 403923 |
| Gene symbol | (Dog) P48749 |
| Gene symbol | CSF2 |
| Canine GM-CSF quantitates canine GM-CSF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine GM-CSF.犬GM-CSF定量测定血清，血浆，上清液中的犬GM-CSF。该检测试剂盒将只识别天然和重组犬GM-CSF。Target information 靶标信息GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).GM-CSF（粒细胞-巨噬细胞集落刺激因子）是一种14.6kDa的造血生长因子，以糖基化和非糖基化的生物活性形式存在，并刺激粒细胞，巨噬细胞，早期巨核细胞和嗜酸性粒细胞祖细胞的发育。 GM-CSF蛋白的活性形式在细胞外被发现为同型二聚体，并且GM-CSF基因已定位在5q31号染色体区域的相关基因簇中，这与5q综合征和5q综合征的间质性缺失有关。急性骨髓性白血病。群集中的其他基因包括编码白介素4、5和13的基因。重组GM-CSF增加造血细胞恢复的能力已成为骨髓移植后患者治疗中的重点领域。最近的研究已经研究了GM-CSF在炎性和自身免疫性疾病中，例如关节炎，与关节炎相关的间质性肺病，肾炎和牛皮癣。在中枢神经系统中，已经在实验性自身免疫性脑脊髓炎（EAE）和多发性硬化症（MS）中研究了GM-CSF的消耗或中和。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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