Fe65 Monoclonal Antibody (OTI3H9)

货号：MA5-27408

规格：100 µL

价格：5956

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Full length human recombinant protein of APBB1 pro

物种：人

宿主：小鼠

抗体亚型：IgG1, kappa

克隆号：OTI3H9

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	1:500-1:2000(WB)

靶标信息The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein, transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.

数据：

Fe65 Antibody (MA5-27408) in WBWestern blot analysis of APBB1 in SH-SY5Y, HeLa cells using 35 µg per lane. Samples were probed with APBB1 (Product # MA5-27408) monoclonal antibody at a dilution of 1:500.

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