Mouse IFN-alpha/beta R2 ELISA Kit/小鼠IFN-alpha / beta R2 ELISA试剂盒
货号:EM39RB,EM39RBX5,EM39RBX10
规格:96 Tests,5X96 Tests,10X96 tests
价格:6641,29884,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:小鼠
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 0.25 ng/mL |
检测范围 | 0.25-50ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | IFNAR2 |
Protein aliases | IFN-alpha/beta receptor 2, IFN-R-2, Interferon alpha/beta receptor 2, interferon receptor 2c, interferon-alpha/beta receptor 2, type I interferon alpha/beta receptor 2a, Type I interferon receptor 2 |
物种(Tested) | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | AI747302, Ifnar-2, Ifnar2 |
Gene ID | (Mouse) 15976 |
Gene symbol | Ifnar2 |
UniProt ID | (Mouse) O35664 |
Mouse IFN-alpha/beta R2 quantitates mouse IFN-alpha/beta R2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IFN-alpha/beta R2.小鼠IFN-alpha / beta R2定量检测血清,血浆,上清液中的小鼠IFN-alpha / beta R2。该检测试剂盒将专门识别天然和重组小鼠IFN-alpha / beta R2。Target information 靶标信息The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.I型干扰素IFN-α和IFN-β是一组在结构和功能上相关的蛋白质,它们被病毒或双链RNA诱导,并通过它们在细胞中赋予抗病毒状态的能力来定义。 IFN-α和IFN-β似乎彼此竞争结合一种共同的细胞表面受体,而免疫IFN(IFN-γ)则结合一种独特的受体。与IFN-alpha / betaR相比,该独特的受体IFN-alphaR对I型干扰素的反应较弱,后者与IFN-beta和几种IFN-alpha亚型结合并对其产生有效反应。 IFN-alpha / betaR表达为两个选择性剪接的转录本,分别称为IFN-alpha / betaRalpha(IFN-alpha / betaR1)和IFN-alpha / betaRbeta(IFN-alpha / betaR2),两者均参与信号转导和配体捆绑。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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