Mouse IL-2 R alpha ELISA Kit/小鼠IL-2 R alpha ELISA试剂盒
货号：EM44RB,EM44RBX5,EM44RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：小鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 10 pg/mL |
| 检测范围 | 10-2,500 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD25 |
| Protein aliases | CD25, IL-2 receptor subunit alpha, IL-2-RA, IL-2R alpha chain, IL-2R subunit alpha, IL2-RA, Interleukin-2 receptor subunit alpha, p55, p55 chain |
物种（Tested） | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CD25, Il2r, Il2ra, Ly-43 |
| Gene ID | (Mouse) 16184 |
| Gene symbol | Il2ra |
| UniProt ID | (Mouse) P01590 |
| Mouse IL-2 R alpha quantitates mouse IL-2 R alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IL-2 R alpha.小鼠IL-2 R alpha定量检测血清，血浆，上清液中的小鼠IL-2 R alpha。该检测试剂盒将专门识别天然和重组小鼠IL-2 Rα。Target information 靶标信息CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.CD25（IL2受体α链/ IL2RA）是一种细胞因子，在T和B淋巴细胞的增殖中起作用。该细胞因子的受体（IL2RA）是异源三聚体蛋白复合物，具有由白介素4（IL4）和白介素7（IL7）共享的γ链。 IL2RA，IL2Rβ链（IL2RB）和IL2Rγ链（IL2RG）构成了高亲和力的IL2受体。同型二聚体IL2RA链产生低亲和力受体，同型二聚体IL2RB链产生中等亲和力受体。 IL2在成熟胸腺细胞中的表达是单等位基因，代表了控制单个基因精确表达的异常调节模式。 IL2主要由成熟的T细胞产生。 IL2作为生长因子，分化因子和细胞死亡调节剂起着重要作用。 IL-2刺激B细胞的增殖，增强自然杀伤细胞的活性，并抑制粒细胞巨噬细胞集落的形成。小鼠中类似基因的定向破坏会导致溃疡性结肠炎样疾病，这提示其在对抗原刺激的免疫反应中起作用。该基因的突变与白细胞介素2受体α缺乏有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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