CD11c Monoclonal Antibody (N418), Functional Grade, eBioscience™/CD11c 单克隆 (N418), 功能抗体, eBioscience™

货号：16-0114-85,16-0114-38,16-0114-025,16-0114-050

规格：500 µg,5 mg,25 mg,50 mg

价格：4085,24089,72266,120443

产品类型：流式抗体

品牌：eBioscience

抗原：CD11c

物种：人/小鼠

宿主：Armenian hamster仓鼠

抗体亚型：IgG

克隆号：N418

荧光染料：其它

_ueditor_page_break_tag_

类型:	一抗(功能抗体）	同型对照：	Armenian Hamster IgG Isotype Control (eBio299Arm), Functional Grade, eBioscience™
浓度：	1 mg/mL	用法：	1 µg/test（Flow）；Assay-Dependent（对照）；Assay-Dependent（FN）

产品详细信息Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.Applications Reported: The N418 antibody has been reported for use in flow cytometric analysis.Applications Tested: The N418 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2 µm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.靶标信息CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.仅用于科研。不用于诊断过程。

数据

CD11c Antibody (16-0114-85) in FlowStaining of C57Bl/6 splenocytes with Anti-Human/Mouse CD45R (B220) APC (Product # 17-0452-82) and 0.5 µg of Armenian Hamster IgG Isotype Control Functional Grade Purified (Product # 16-4888-81) (left) or 0.5 µg of Anti-Mouse CD11c Functional Grade Purified (right) followed by Anti-Armenian Hamster IgG FITC (Product # 11-4111). Cells in the lymphocyte gate were used for analysis.

推荐产品：

二抗荧光二抗免疫组化一抗标签抗体

参考文献：

流式1.Frontiers in immunologyTpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells."Published figure using CD11c monoclonal antibody (Product # 16-0114-85) in Flow Cytometry"2.Frontiers in immunologyFcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells."Published figure using CD11c monoclonal antibody (Product # 16-0114-85) in Flow Cytometry"3.Nature metabolismKnockdown ofAnt2Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity."Published figure using CD11c monoclonal antibody (Product # 16-0114-85) in Flow Cytometry"ICC4.Biochimica et biophysica actaAntigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis."Published figure using CD11c monoclonal antibody (Product # 16-0114-85) in Flow Cytometry"IF5.International journal of molecular medicineIdentification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy."Published figure using CD11c monoclonal antibody (Product # 16-0114-85) in Immunofluorescence"

技术参数

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://biorod.cn/thread-26497.htm