CD90.1 (Thy-1.1) Monoclonal Antibody (HIS51), PerCP-Cyanine5.5,

货号：45-0900-80,45-0900-82

规格：25 ug ,100 µg

价格：1038,2630

产品类型：流式抗体

品牌：eBioscience

抗原：CD90.1 (Thy-1.1)

物种：人/小鼠/大鼠

宿主：小鼠

抗体亚型：IgG2a, kappa

克隆号：HIS51

荧光染料：Alexa Fluor 488

类型:	单抗	同型对照：	Mouse IgG2a kappa Isotype Control (eBM2a), PerCP-Cyanine5.5
浓度：	0.2 mg/mL	用法：	0.06 µg/test(Flow)

产品详细信息Description: The HIS51 monoclonal antibody reacts with rat CD90 and cross-reacts with mouse CD90.1, a GPI-linked membrane molecule. In the rat, CD90 is expressed by hematopoietic stem cells, immature B cells, thymocytes, recent thymic emigrants, neurons, inflammed endothelia and other cell types. In the CD90.1-expressing mouse strains, PL and AKR, CD90 is expressed by early hematopoietic cells in the bone marrow, thymocytes and mature T cells.Applications Reported: This HIS51 antibody has been reported for use in flow cytometric analysis.Applications Tested: This HIS51 antibody has been tested by flow cytometric analysis of rat splenocytes. This can be used at less than or equal to 0.06 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. It is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. Thy 1 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

数据

CD90.1 (Thy-1.1) Antibody (45-0900-80) in FlowStaining of rat thymocytes with 0.03 µg of Mouse IgG2a K Isotype Control PerCP-Cyanine5-5 (Product # 45-4724-82) (open histogram) or 0.03 µg of Anti-Mouse/Rat CD90-1 (Thy-1-1) PerCP-Cyanine5-5 (filled histogram). Total viable cells were used for analysis.

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参考文献

1. Journal of immunology (Baltimore, Md. : 1950)Developmental Progression and Interrelationship of Central and Effector Regulatory T Cell Subsets.2. Journal of immunology (Baltimore, Md. : 1950)Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.3. The Journal of clinical investigationMutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.4. Experimental and therapeutic medicineTanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation ofCx37,Cx40andCx43.5. Nature communicationsDiabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.

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