Rabbit anti Human glutamate decarboxylase 1 antibody
货号：VPA00827
规格：100 µl
价格：3171
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：glutamate decarboxylase 1
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human glutamate decarboxylase 1 antibodyrecognizes glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, GAD-67 and GAD1.GAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of GAD1 results in two products, the predominant 67 kDa form and a less-frequent 25 kDa form (provided by RefSeq, Jul 2008).Rabbit anti Human glutamate decarboxylase 1 antibody detects a band of 67 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Rabbit polyclonal antibody purified by affinity chromatography on immunogen |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.09% Sodium Azide2% Sucrose |
| Immunogen | Synthetic peptide corresponding to a portion of the N terminal region of human glutamate decarboxylase 1 |
| Acknowledgements | Recombinant protein of human ASNS |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 多克隆抗体
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