goat anti FUMARatE HYDRatASE
货号:VPA00124
规格:100 µl
价格:3613
产品类型:免疫组化一抗
品牌:Bio-Rad
物种:人
宿主:山羊
抗体亚型:IgG
荧光染料:Purified
产品介绍 | | |
Goat anti Human fumarate hydratase antibodyrecognizes the fumarate hydratase, mitochondrial, also known simply as Fumarase.Fumarase, encoded by the FH gene, is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in FH can cause fumarase deficiency and lead to progressive encephalopathy (provided by RefSeq, Jul 2008).Goat anti Human fumarate hydratase antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Goat polyclonal antibody purified by affinity chromatography. |
Buffer Solution | TRIS buffered saline. |
Preservative Stabilisers | 0.02% Sodium Azide (NaN3) 0.5% BSA |
Immunogen | Peptide with the sequence C-HPNDHVNKSQSSND, from the internal region of the protein sequence. |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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