Mouse anti Human CD36 antibody, clone SMØ
货号：MCA722T,MCA722GA,MCA722
规格：25 µg,0.1 mg,0.2 mg
价格：935,2023,3315
产品类型：流式抗体
品牌：Bio-Rad
抗原：CD36
物种：人
宿主：小鼠
抗体亚型：IgM
克隆号：SMØ
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human CD36 antibody, clone SMØrecognizes the CD36 antigen, an ~88 kDa cell surface glycoprotein expressed by platelets, monocytes/macrophages and also by some microvascular endothelium and erythroid precursors.CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Mouse anti Human CD36 antibody, clone SMØ partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this antibody may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team.Mouse anti Human CD36 antibody, clone SMØ is also reported to block interaction of oxidized low-density lipoprotein (OXLDL) with CD36 (Sugiharaet al.1992). |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgM - liquid |
| Preparation | Purified IgM prepared by ammonium sulphate precipitation from tissue culture supernatant |
| Buffer Solution | Phosphate buffered saline |
| Immunogen | Human tonsil cells and peripheral blood mononuclear cells. |
| Preservative Stabilisers | 0.09%Sodium Azide |
| Carrier Free | Yes |
| Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
| Fusion Partners | Spleen cells from immunised mice were fused with cells of the NSI mouse myeloma line. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store at +4℃.DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | 1/50Pack Size: 0.2 mg1/10Pack Size: 0.1 mg | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 推荐产品 |
| Description | Product Code | Applications | Pack Size |
| Mouse IgM Negative Control | MCA692 | F | 100 Tests |
| 文献 |
| 1.Hogg, N.et al.(1984) Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.Immunology. 53 (4): 753-67.2.Sarigianni, M.et al.(2010) Effect of leptin and insulin resistance on properties of human monocytes in lean and obese healthy participants.Angiology. 61: 768-74.3.Sugihara, K.et al.(1992) Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells.Blood. 80 (10): 2634-42.4.Biswas, A.K.et al.(2007) Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.PLoS Pathog. 3: 1271-80. |
技术参数 产品应用 Flow
产品类型 Monoclonal Antibody
推荐用于 Flow
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-30394.htm
QQ:1749072012