Mouse anti Human alpha Fetoprotein antibody, clone 4A3
货号：MCA2753
规格：0.2 mg
价格：3018
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：alpha Fetoprotein
物种：人
宿主：小鼠
抗体亚型：IgG2a
克隆号：4A3
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human alpha Fetoprotein antibody, clone 4A3recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults.Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down’s syndrome.Mouse anti Human alpha Fetoprotein antibody, clone 4A3 does not cross-react with human albumin. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant |
| Buffer Solution | Phosphate buffered saline |
| Immunogen | Purified human alpha fetoprotein. |
| Fusion Partners | Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. |
| Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | 1/50 | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| Description | Product Code | Applications | Pack Size |
| Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) | STAR117A | F | 0.5mg |
| 文献 |
| 1.Wang, X.W. & Xu, B. (1998) Stimulation of tumor-cell growth by alpha-fetoprotein.Int J Cancer. 75 (4): 596-9. |
技术参数 产品应用 Elisa
产品类型 Monoclonal Antibody
推荐用于 Elisa
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