Rat anti Human CDw210a, clone 3F9
货号：MCA2255GA
规格：0.1 mg
价格：2066
产品类型：流式抗体
品牌：Bio-Rad
抗原：CDw210a
物种：人
宿主：大鼠
抗体亚型：IgG2a
克隆号：3F9
荧光染料：Purified
| 产品介绍 | | |
| Rat anti Human CDw210a, clone 3F9recognizes human CDw210a, a 90-110 kDa glycoprotein, also known as Interleukin-10 receptor 1 (IL-10R1).CDw210a is expressed on T cells, NK cells, monocytes and dendritic cells, although surface expression may be low.Intracellular expression of CDw210a increases during dendritic cell maturation, while surface CDw210a expression decreases (Corintiet al.2001) .Rat anti Human CDw210a, clone 3F9 functions as a blocking antibody(Liuet al.1997). |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Buffer Solution | Phosphate buffered saline |
| Immunogen | Soluble human CDw210a |
| Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
| Preservative Stabilisers | 0.09%Sodium Azide |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| 文献 |
| 1.Liu, Y.et al.(1997) The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor.J Immunol. 158 (2): 604-13.2.O7#39;Farrell, A.M.et al.(1998) IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways.EMBO J. 17 (4): 1006-18.3.Elbim, C.et al.(2001) Intracellular pool of IL-10 receptors in specific granules of human neutrophils: differential mobilization by proinflammatory mediators.J Immunol. 166 (8): 5201-7.4.Fayette, J.et al.(1997) Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2.J Exp Med. 185 (11): 1909-18. |
技术参数 产品应用 Flow
产品类型 Monoclonal Antibody
推荐用于 Flow
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