Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148
货号：MCA2086
规格：0.2 mg
价格：3315
产品类型：流式抗体
品牌：Bio-Rad
抗原：CD18 (Activation Epitope)
物种：人
宿主：小鼠
抗体亚型：IgG1
克隆号：MEM-148
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148recognizes an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Reconstitution | Reconstitute with 1.0 ml distilled waterCare should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G |
| Buffer Solution | Phosphate buffered saline |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Prior to reconstitution store at +4℃. Following reconstitution store at +4℃.DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| Rat IgG2a Negative Control:RPE | STAR117A | F | 0.5mg |
| 文献 |
| 1.Drbal, K.et al.(2001) A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.Blood. 98 (5): 1561-6.2.Luissint, A.C.et al.(2008) JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.J Cell Biol. 183 (6): 1159-73.3.Feng, C.et al.(2011) Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1.J Leukoc Biol. 90: 313-21.4.Anogianaki, A.et al.(2007) Capsaicin an irritant anti-inflammatory compound.J Biol Regul Homeost Agents. 21: 1-4. |
技术参数 产品应用 Flow;WB
产品类型 Monoclonal Antibody
推荐用于 Flow;WB
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