产品介绍 | | |
Rat anti Mouse CD137 antibody, clone LOB12recognizes murine CD137 also known as Tumor necrosis factor receptor superfamily member 9, T-cell antigen 4-1BB or 4-1BB ligand receptor. CD137 is a 256 amino acid ~28 kDa single pass type I transmembrane glycoprotein.CD137 is expressed by activated T lymphocytes, but not by resting cells. |
产品详情 | | |
Target Species | Rat |
Product Form | Purified IgG - liquid |
Preparation | Purified IgG prepared by affinity chromatography from tissue culture supernatant |
BufferSolution | TRIS buffered saline |
Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
Immunogen | Murine CD137 human Fc fusion protein |
Approx. Protein Concentrations | IgG concentration 1 mg/ml |
Regulatory | For research purposes only |
Guarantee | 12 monthsfrom dateof despatch |
存储条件 | | |
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Flow Cytometry | √ | 1/10 | 1/50 |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude itsuse in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells in 100ul. |
同型 |
Description | Product Code | Applications | Pack Size |
Rat IgG2a Negative Control | MCA1212 | Flow;ELISA | 1 mL |
文献 |
1.Taraban, V.Y.et al.(2002) Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses.Eur J Immunol. 32 (12): 3617-27. |