Rabbit anti Human IGFBP-7 antibody
货号：AHP1282
规格：0.1 mg
价格：4063
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：IGFBP-7
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human IGFBP-7 antibodyrecognizes human IGFBP-7 (insulin-like growth factor binding protein-7), also known as mac25, a 256 amino acid secreted protein and member of a growing family of IGFBPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II.IGFBP-7 is widely expressed throughout normal tissues, but is also expressed in many tumour types at an increased or reduced level, and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation, by its possible affects on the actions of parathyroid hormone (PTH) and cortisol. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - lyophilized |
| Antiserum Preparation | Antisera to human IGFBP-7 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | None present. |
| Immunogen | Recombinant human IGFBP-7 |
| Approx. Protein Concentrations | IgG concentration 1.0mg/ml after reconstitution. |
| Regulatory | For research purposes only |
| Guarantee | 6 months from date of despatch |
| 存储条件 | | |
| Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | 0.1 | 0.2ug/ml |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E,WB | 1mg |
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C,E,WB | 1mg |
| 文献 |
| 1.Ruan, W.J.et al.(2006) IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1.J Zhejiang Univ Sci B. 7 (11): 929-32.2.Pereira, R.C. & Canalis, E. (1999) Parathyroid hormone increases mac25/insulin-like growth factor-binding protein-related protein-1 expression in cultured osteoblasts.Endocrinology. 140 (5): 1998-2003. |
技术参数 产品应用 elisa；wb
产品类型 Polyclonal Antibody
推荐用于 elisa；wb
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