Goat anti Huma MMP7 antibody
货号：AHP1081
规格：0.1 mg
价格：6095
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：MMP7
物种：人
宿主：山羊
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Goat anti Huma MMP7 antibodyrecognises matrix metalloproteinase 7 (MMP7), a ~30 kDa member of the MMP family. MMP's are secreted as inactive zymogens which are activated when proteolytically cleaved by extracellular proteinases. They are involved in processes such as embryonic development, reproduction and tissue remodelling where they breakdown the extracellular matrix. This action is also exploited by diseases processes including arthritis and metastasis. MMP7 degrades casein, fibronectin, gelatin types I, III, IV, V, and activates procollagenase. This metalloproteinase has been identified as an activator of the Notch signalling pathway, and is also involved in wound healing and the regulation of defensins in intestinal mucosa. |
| 产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Antiserum Preparation | Antisera to human MMP7 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. |
Buffer Solution | TRIS buffered saline |
Preservative Stabilisers | 0.02%Sodium Azide 0.5%Bovine Serum Albumin |
Approx. Protein Concentrations | Peptide sequence C-QKLYGKRSNSRKK corresponding to the C-terminus of MMP7 (NP_002414.1). |
Immunogen | Peptide sequence C-QKLYGKRSNSRKK corresponding to the C-terminus of MMP7 (NP_002414.1). |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
ELISA | √ | | 1/64000 |
Western Blotting | √ | 0.03 | 0.1ug/ml |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.- Western Blotting
- AHP1081 detects a band of approximately 28kDa in human breast, ovary and placenta cell lysates. A minimum incubation time of 1 hour is recommended with this antibody
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| 二抗相关产品 |
Description | Product Code | Applications | Pack Size |
| Rabbit anti Goat IgG (Fc):FITC | STAR122F | Flow | 1 mg |
| Rabbit anti Goat IgG (Fc):HRP | STAR122P | C;E;WB | 1 mg |
| 数据 |
| Western blotting analysis of human breast lysate (35μg protein in RIPA buffer) using Goat anti Human MMP7 antibody (AHP1081) at 0.03μgml-1. Primary incubation was 1 hour. Signal was detected by chemiluminescence. |
| 文献 |
| 1. Gaire, M.et al.(1994) Structure and expression of the human gene for the matrix metalloproteinase matrilysin.J Biol Chem. 269 (3): 2032-40. |
技术参数 产品应用 ELISA;WB
产品类型 Polyclonal Antibody
推荐用于 ELISA;WB
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