Rabbit anti Rat NMDA Receptor NR2B
货号：6870-1109
规格：10 µg
价格：8628
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：NMDA Receptor NR2B
物种：大鼠
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Rat NMDA Receptor NR2B antibodyrecognizes the ~180 kDa NMDA (N-methyl-D-aspartate) receptor NMDAR2B subunit.NMDA receptors are a class of ionotropic glutamate receptors. NMDA channels have been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), or NMDAR2D (GRIN2D). |
| 产品详情 | | |
Target Species | Rat |
Product Form | Purified IgG - lyophilized |
Preparation | Purified IgG prepared by affinity chromatography |
Buffer Solution | Ammonium bicarbonate |
Preservative Stabilisers | None present |
Reconstitution | Reconstitute with 50µl of Phosphate buffered saline |
Immunogen | C-terminal fusion protein of Rat NMDAR2B (30kDa) corresponding to amino acids 984-1104. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Prior to reconstitution store at +4℃.After reconstitution store at -20℃.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Immunohistology - Frozen | √ | 1/1000 | 1/2000 |
Immunoprecipitation | √ | | |
Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Technical Advice3 µl of antibody will quantitatively immunoprecipitate all NMDAR2B in 200 µg of rat brain. Optimal working dilutions must be determined by the end user.Histology Positive Control TissueHippocampus. |
| 二抗相关产品 |
Description | Product Code | Applications | Pack Size |
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E;WB | 1 mg |
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| 文献 |
| 1. Maliszewska-Cyna, E.et al.(2010) Diminished prevalence but preserved synaptic distribution of N-methyl-D-aspartate receptor subunits in the methyl CpG binding protein 2(MeCP2)-null mouse brain.Neuroscience. 168: 624-322. Asaka, Y.et al.(2006) Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome.Neurobiol Dis. 21: 217-27.3. Grosshans, D.R. and Browning, M.D. (2001) Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor.J Neurochem. 76: 737-44. |
技术参数 产品应用 IHC(F);IP;WB
产品类型 Polyclonal Antibody
推荐用于 IHC(F);IP;WB
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