产品介绍 |
| Rabbit anti Human TGN46 antibodyrecognizes Trans-Golgi network integral membrane protein 2, also known as TGN46, TGN38 homolog or Trans-Golgi network protein TGN51. TGN46 is a 480 amino acid ~110kDa single pass type I transmembrane glycoprotein associated with the trans golgi network membrane. TGN46 has been reported as being the best available marker for human trans-Golgi network. |
产品详情 |
Target Species | Human |
Species Cross-Reactivity | Target Species | Cross Reactivity |
| Primate | √ |
| N.B. Antibody reactivity and working conditions may vary between species. |
Product Form | Serum - liquid |
Antiserum Preparation | Antisera to human TGN46 were raised by repeated immunisation of rabbits with highly purified recombinant human TGN46. |
Preservative Stabilisers | <0.1% Sodium Azide (NaN3)1% Bovine Serum Albumin50% Glycerol |
Immunogen | Recombinant human TGN46. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 |
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
应用 |
Application Name | Verified | Min Dilution | Max Dilution |
Immunofluorescence1 | √ | 1/50 | 1/100 |
Western Blotting | √ | 1/500 | 1/000 |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.- 1Fixation of tissues with 3% paraformaldehyde or methanol is recommended prior to using this antibody on immunofluorescence.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
可用二抗 |
Description | Product Code | Applications | Pack Size |
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
相关产品 |
Description | Product Code | Applications | Pack Size |
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
文献 |
| 1.Prescott, A.R.et al.(1997) Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.Eur J Cell Biol. 72 (3): 238-46.2.Ponnambalam, S.et al.(1996) Primate homologues of rat TGN38: primary structure, expression and functional implications.J Cell Sci. 109 ( Pt 3): 675-85.3.Vuillier, F.et al.(2005) Lower levels of surface B-cell-receptor expression in chronic lymphocytic leukemia are associated with glycosylation and folding defects of the mu and CD79a chains.Blood. 105 (7): 2933-40.4.Cerqueira, C.et al.(2015) Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells.J Virol. 89 (14): 7038-52.5.Striebinger, H.et al.(2016) Subcellular Trafficking and Functional Relationship of the HSV-1 Glycoproteins N and M.Viruses. 8 (3): pii: E83.6.Sandri, C.et al.(2012) The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.Cell Res. 22 (10): 1479-501.7.Aydin, I.et al.(2014) Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses.PLoS Pathog. 10 (5): e1004162. |
QQ:1749072012