TRA-1-60 Monoclonal Antibody (cl.A)

货号：411000

规格：100 µg

价格：4809

产品类型：流式抗体

品牌：Thermo Fisher

物种：人

宿主：小鼠

抗体亚型：IgM

克隆号： cl.A

荧光染料：其它

类型:	单抗	同型对照：
浓度：	0.5mg/mL	用法：	Assay-dependent(WB)；Assay-dependent(ICC/IF)

靶标信息TRA-1-60 is a cell surface antigen, expressed along with SSEA-3, SSEA-4 and TRA-1-81 in human embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). These surface markers are lost during the differentiation process. In contrast, SSEA-1 is absent in undifferentiated human stem cells but is present on the cell surface after retinoic acid mediated differentiation.

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参考文献：

1eLifeRapid DNA replication origin licensing protects stem cell pluripotency."41-1000 was used in Western Blotting to demonstrate that rapid origin licensing is an intrinsic characteristic of stem cells that contributes to pluripotency maintenance."AuthorsMatson JP,Dumitru R,Coryell P,Baxley RM,Chen W,Twaroski K,Webber BR,Tolar J,Bielinsky AK,Purvis JE,Cook JG2Nature protocolsEfficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells."41-1000 was used in western blot to describe a method to generate cystic fibrosis transmembrane conductance regulator protein-expressing airway epithelial cells from human pluripotent stem cells"AuthorsWong AP,Chin S,Xia S,Garner J,Bear CE,Rossant J3.International journal of cancerComparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours.AuthorsAndrews PW,Casper J,Damjanov I,Duggan-Keen M,Giwercman A,Hata J,von Keitz A,Looijenga LH,Millán JL,Oosterhuis JW,Pera M,Sawada M,Schmoll HJ,Skakkebaek NE,van Putten W,Stern P4Journal of stem cells & regenerative medicineMouse iPSC generated with porcine reprogramming factors as a model for studying the effects of non-silenced heterologous transgenes on pluripotency."41-1000 was used in Immunocytochemistry to evaluate the ability of transposon-based vectors with porcine pluripotency factors to reprogram mouse foetal fibroblasts to pluripotency."5.Nature methodsIsolation of human iPS cells using EOS lentiviral vectors to select for pluripotency."41-1000 was used in flow cytometry and immunocytochemistry to report the first selection system for the isolation of human induced pluripotent stem cells"

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