Dexamethasone

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Dexamethasone

货号:5000222-500,5000222-5

规格:500mg,5g

价格:495,2695

产品类型:小分子化合物

品牌:Biogems

Dexamethasone is a synthetic anti-inflammatory and immunosuppressant steroid. It has a stronger affinity for the glucocorticoid receptor than the natural hydrocortisone ligand. Dexamethasone is reported to inhibit mature dendritic cell differentiation and to promote the differentiation of human mesenchymal cells.

Additional Information

Applications

FA

Synonyms:

Decaject, Decameth, Decaspray, Dexasone, Hexadecadrol

Formulation:

Crystalline solid

Chemical Name:

(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

Molecular Formula:

C22H29FO5

Molecular Weight:

392.5

CAS Number

50-02-2

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Haynesworth, S. E., Baber, M. A., & Caplan, A. I. (1996). Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α.Journal of cellular physiology,166(3), 585-592.

Han, J., Thompson, P., & Beutler, B. (1990). Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.The Journal of experimental medicine,172(1), 391-394.

Larsson, E. L. (1980). Cyclosporin A and dexamethasone suppress T cell responses by selectively acting at distinct sites of the triggering process.The Journal of Immunology,124(6), 2828-2833.

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